AHCC

Common name: Active Hexose Correlated Compound

Botanical name: Basidiomycetes

Parts used and where grown

AHCC™ is a newly developed “functional food” made through the hybridization of several kinds of mushrooms belonging to the Basidiomycetes family, including shiitake (Lentinula edodes), cultured in a liquid medium. The mushroom's sources and details of methods of preparation have not been fully disclosed.

AHCC has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings	Health Concerns
	Cancer
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Historical or traditional use (may or may not be supported by scientific studies)

AHCC was not used in traditional medicine. The mushrooms of the type from which AHCC is made were historically used as tonics and for chronic infections, anaemia, and a variety of other conditions.¹

Active constituents

AHCC consists of polysaccharides, particularly low molecular weight alpha-1,3-glucans, amino acids, and minerals.

How much is usually taken?

Studies have typically administered 3 grams per day orally.

Are there any side effects or interactions?

In the studies in which AHCC was given to people with cancer, no side effects or drug interactions were observed. However, thorough studies establishing its safety have not been conducted. There are no reports that AHCC is contraindicated in any condition. Use in pregnancy and lactation have not been studied.

At the time of writing, there were no well-known drug interactions with AHCC.

References
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1. Hobbs CR. Medicinal Mushrooms: An exploration of tradition, healing & culture, 3rd ed. Santa Cruz, CA: Botanica Press, 1995.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2007.

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