Hyssop

Botanical name: Hyssopus officinalis

Parts used and where grown

Hyssop reportedly originated in the area around the Black Sea in central Asia and today is widely cultivated in other arid regions, partly because it thrives even in the most desolate soils. Hyssop’s fragrant flowers and leaves are used as medicine.

Hyssop has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings

Health Concerns

Asthma

Colic

Common cold/pharyngitis

Cough

Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars

Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star

For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

Historical or traditional use (may or may not be supported by scientific studies)

The most common uses of hyssop in traditional herbalism have been to relieve chest congestion and coughs, to soothe sore throats, and to act as a mild sedative.¹ Some herbalists consider it stronger for relieving wind or intestinal cramping than for easing a cough.² In addition to using hyssop for the above conditions, early 20th century Eclectic physicians (doctors who recommended herbs) in the United States used the herb topically to soothe burned skin.³

Active constituents

Due to the presence of volatile oil constituents in hyssop, it may provide relief for mild irritations of the upper respiratory tract that accompany the common cold. The expectorant action of hyssop’s volatile oil may partially explain its traditional use for coughs, asthma, and bronchitis.⁴ The volatile oils are also thought to contribute to hyssop’s carminative actions and use for mild cramping and discomfort in the digestive tract. The German Commission E has not approved hyssop for any medical indication.⁵ Test tube studies have found that certain fractions of hyssop (one being a polysaccharide designated as MAR-10) may inhibit the activity of the human immunodeficiency virus (HIV).⁶ ⁷ Yet, there have been no studies in humans to determine whether hyssop or any of its constituents are effective in treating HIV infection or AIDS.

How much is usually taken?

Hyssop may be taken as a tea or tincture. The tea is prepared by infusing 2–3 teaspoons of herb in one cup (250 ml) of hot water for ten to fifteen minutes. Three cups can be drunk per day. Alternatively, 1–4 ml of tincture can be taken three times per day.⁸ If hyssop is being used to help soothe a sore throat, gargle with the tea or tincture before swallowing. The essential oil should never be used at a level higher than 1–2 drops per day internally, though more can be used topically on unbroken skin. One teaspoon (5 grams) of hyssop herb steeped in 1 cup (250 ml) hot water in a closed vessel for 15–20 minutes, then given in sips from a bottle over a period of 2–3 hours, may help calm colic.

Are there any side effects or interactions?

Tea and tincture of hyssop are unlikely to cause adverse effects.⁹ Although, the volatile oil, particularly its constituent pinocamphone, has been reported to cause seizures in laboratory animals as well as in humans when taking more than 10 drops in a day or a child taking 2–3 drops over several days.¹⁰ For this reason, the volatile oil should be used with extreme caution and is not recommended for those with epilepsy or any other seizure disorder. The herb is not recommended during pregnancy.¹¹

At the time of writing, there were no well-known drug interactions with hyssop.

References
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1. Castleman M. The Healing Herbs. New York: Bantam, 1991, 323–7.

2. Weiss RF. Herbal Medicine. Gothenburg, Sweden: Ab Arcanum and Beaconsfield, UK: Beaconsfield Publishers Ltd, 1985, 206.

3. Castleman M. The Healing Herbs. New York: Bantam, 1991, 323–7.

4. Gruenwald J, Brendler T, Jaenicke C (eds). PDR for Herbal Medicines. Montvale, NJ: Medical Economics, 2000, 414–5.

5. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 338–9.

6. Gollapudi S, Sharma HA, Aggarwal S, et al. Isolation of a previously unidentified polysaccharide (MAR-10) from Hyssop officinalis that exhibits strong activity against human immunodeficiency virus type 1. Biochem Biophys Res Commun 1995;210:145–51.

7. Kreis W, Kaplan MH, Freeman J, et al. Inhibition of HIV replication by Hyssop officinalis extracts. Antiviral Res 1990;14:323–37.

8. Hoffmann D. The New Holistic Herbal. New York: Barnes & Noble, 1990, 207.

9. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 338–9.

10. Tisserand R, Balacs T. Essential Oil Safety: A Guide for Health Care Professionals. Edinburgh: Churchill Livingstone, 1995, 67.

11. McGuffin M, Hobbs C, Upton R, Goldberg A (eds). American Herbal Product Association’s Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 63.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2007.