Lindane

Also indexed as: Hexit®, Kwell® Shampoo, PMS-Lindane®

Lindane lotion is used topically to treat scabies;lindane shampoo is used to treat head and pubic lice. They are used in situations where treatment with other drugs has failed or cannot be tolerated by the individual.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, a herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

May be Beneficial: Side effect reduction/prevention—Taking these supplements may help reduce the likelihood and/or severity of a potential side effect caused by the medication.	Vitamin E*
Depletion or interference	None known
Supportive interaction	None known
Reduced drug absorption/bioavailability	None known
Adverse interaction	None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

Vitamin E
Test tube studies reveal that vitamin E protects white blood cells from damage caused by lindane.¹ Lindane is known to promote the formation of tumours,² and more research is needed to determine whether vitamin E, when applied at the same time as lindane, can prevent this adverse effect.

Interactions with Foods and Other Compounds

Oils
Applying oils, creams, and ointments at the same time as lindane may enhance the absorption of the drug through the skin.³ Therefore, to avoid side effects, other drugs and herbal formulas in cream or ointment form should be applied at other times during the day.

References
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1. Podstawka U, Grabarczyk M, Kopec-Szlezak J. Vitamin E protects human leucocytes against toxic effects of lindane in vitro. Mater Med Pol 1991;23:285–9.

2. Dich J, Zahn SH, Hanberg A, Adami HO. Pesticides and cancer. Cancer Causes Control 1997;8:420–43.

3. Sifton DW, ed. Physicians Desk Reference. Montvale, NJ: Medical Economics Company, Inc.,2000, 504–5.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2007.

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Interactions with Dietary Supplements

Interactions with Foods and Other Compounds