Loratadine

Also indexed as: Boots Hayfever Relief®, Claritin®, Clarityn Allergy®, Clarityn®

Combination drug: Claritin®-D

Loratadine is a selective antihistamine used to relieve allergic rhinitis (seasonal allergy) symptoms, including sneezing, runny nose, itching, and watery eyes. It is also used to treat people with idiopathic urticaria. Loratadine is available alone and in a combination product.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, a herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Depletion or interference	None known
Side effect reduction/prevention	None known
Supportive interaction	None known
Reduced drug absorption/bioavailability	None known
Adverse interaction	None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Food
Food slows the absorption of loratadine and also increases the total amount of the drug absorbed.¹ It is recommended that loratadine be taken on an empty stomach.²

Alcohol
Selective antihistamines, including loratadine, may cause drowsiness or dizziness, although it is less likely than with nonselective antihistamines.³ Alcohol can intensify drowsiness and dizziness, increasing the risk of accidental injury. People taking loratadine should use alcohol only with caution.

References
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1. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.

2. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.

3. Threlkeld DS, ed. Respiratory Drugs, Antihistamines. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1998, 194b.

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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or chemist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires March 2007.

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Interactions with Foods and Other Compounds