Also indexed as: Imigran®, Imitrex®
Sumatriptan is a member of the selective serotonin receptor agonist family of drugs used to
treat, but not prevent, migraine headaches.
Sumatriptan is available in injection, nasal spray, and oral tablet forms.
Summary of
Interactions with Vitamins, Herbs, and Foods
In some cases, a herb or supplement may appear in more than one category, which may seem
contradictory. For clarification, read the full article for details about the summarized
interactions.
Avoid: Adverse interaction—Avoid these supplements when taking this
medication because taking them together may cause undesirable or dangerous results. |
5-Hydroxytryptophan (5-HTP)*
L-tryptophan*
|
| Depletion or interference |
None known
|
| Side effect reduction/prevention |
None known
|
| Supportive interaction |
None known
|
| Reduced drug
absorption/bioavailability |
None known
|
An asterisk (*) next to an item in the summary indicates that the
interaction is supported only by weak, fragmentary, and/or contradictory scientific
evidence.
Interactions with Dietary Supplements
5-Hydroxytryptophan
(5-HTP) and L-tryptophan
Sumatriptan works by stimulating serotonin receptors in the brain. 5-HTP and L-tryptophan are
converted to serotonin in the brain, and taking them with sumatriptan could increase
sumatriptan-induced side effects. However, no interactions have yet been reported with
sumatriptan and 5-HTP or L-tryptophan.
Interactions with Foods and Other Compounds
Food
Sumatriptan tablets may begin to work faster when taken with fluid on an empty stomach at the
first sign of migraine.1
2
References
(To view, roll mouse over heading; to hide, click on heading)
1. Threlkeld DS, ed. Central Nervous System Drugs, Agents for Migraine,
Serotonin 5-HT1 Receptor Agonists. In Facts and Comparisons Drug Information. St.
Louis, MO: Facts and Comparisons, Jun 1996, 256a.
2. Holt GA. Food & Drug Interactions. Chicago: Precept
Press, 1998, 253.
Copyright © 2006 Healthnotes, Inc. All rights reserved.
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with Vitamins and Herbs
The information presented in Healthnotes is for informational purposes
only. It is based on scientific studies (human, animal, or in vitro), clinical
experience, or traditional usage as cited in each article. The results reported may not
necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over the counter medication is also available. Consult your doctor,
practitioner, and/or chemist for any health problem and before using any supplements or before
making any changes in prescribed medications. Information expires March 2007.
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