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Chitosan

Illustration

What is it?

Chitosan is a polysaccharide found in the shells of crustaceans.

Like dietary fibre, chitosan is not digestible but may have beneficial effects on the gastrointestinal tract. Chitosan may also have an effect on the type of bacteria living in the intestines or on the action of these bacteria.

Where is it found?

Chitosan is extracted from the shells of crustaceans, such as shrimp and crab.

Chitosan has been used in connection with the following conditions (refer to the individual health concern for complete information):

Science Ratings Health Concerns
1Star

High cholesterol

Kidney failure

Weight loss

3Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1Star For a herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.
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Who is likely to be deficient?

Chitosan is not an essential nutrient, so deficiencies do not occur.

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How much is usually taken?

Most human research has used 3–6 grams per day with meals.

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Are there any side effects or interactions?

While no long-term studies of the effects of chitosan on human health have been done, animal studies suggest that this compound could inhibit the absorption of minerals and fat-soluble vitamins. Adverse effects on the growth of children and on the outcome of pregnancy are also possible.1 In addition, although chitosan-included alterations in intestinal flora are believed to be beneficial, the possibility that these changes may have negative long-term consequences has not been ruled out. People with intestinal malabsorption syndromes should not use chitosan.

At the time of writing, there were no well-known drug interactions with chitosan.

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References
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1. Koide SS. Chitin-chitosan: properties, benefits and risks. Nutr Res 1998;18:1091–101 [review].

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