Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic derivative of thiamin (vitamin B1). Benfotiamine is fat-soluble, more bioavailable, and physiologically active than thiamine.* Benfotiamine helps maintain healthy cells in the presence of blood glucose, supports against oxidative stress, and supports healthy aging.
Doctor's Best Benfotiamine + Alpha-Lipoic Acid helps maintain healthy cells in the presence of blood glucose and provides support against oxidative stress and supports healthy aging.*
Benfotiamine helps protect oxidative stress induced by advanced glycation end-products.
Alpha-Lipoic Acid supports the body's defense against free radicals and recycles antioxidant nutrients such as Vitamin C and Vitamin E.*
Alpha-lipoic acid is a sulfur-containing fatty acid that performs vitamin-like roles in the body. Because it is soluble in both water and fat, alpha-lipoic acid is sometimes referred to as the "universal antioxidant".
Non-GMO, Gluten Free, Vegetarian, Vegan
Benfotiamine raises the blood level of thiamin pyrophosphate, the biologically active coenzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Benfotiamine was shown to cause, on average, a 5-fold greater increase in blood thiamine levels than thiamin mononitrate, with a concomitant greater thiamine concentration in red blood cells. Benfotiamine readily passes through intestinal cells and is converted into thiamin. Alpha-lipoic acid is a key factor in the cellular process that metabolizes glucose for energy production. Aging is accompanied by a decreased ability of the liver to recycle ascorbic acid following oxidative stress. R-lipoic acid, after two weeks of supplementation to aged rats, reversed the age-related impairment of ascorbic acid recycling and concentration in liver cells. Aging is associated with oxidative stress in the brain. The brain's high rate of metabolism and its long-lived neurons make it particularly vulnerable to oxidative stress. Since alpha-lipoic acid interrupts cellular oxidative processes in both its oxidized and reduced forms, it plays a modulatory role in the brain and nervous system.