Our Double Strength SAM-e 400 contains 400 mg of active Soloesse SAM-e in each tablet. Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e available providing slow and targeted release for improved GI tolerance and absorption. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.
Doctor's Best SAMe is proven to enhance mood and promote cognitive health. It is essential for the healthy metabolism of the major brain transmitters' dopamine, serotonin and norepinephrine. In addition, SAMe promotes joint comfort and mobility and supports liver health and detoxification. SAMe effectiveness has been published in 18 controlled human trials published over 40 years. Doctor's Best SAMe uses pharmaceutical grade materials. SAMe is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. SAMe optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed). Effectiveness of SAMe has been backed by at least 18 controlled human trials published over almost four decades.
S-Adenosyl Methionine (SAMe) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.
SAM-e is a biological compound found in every living cell of the human body, vital to their function, stability and activity and involved in more than one hundred biochemical reactions and specific processes. SAMe helps promote healthy mood. So if your body is not producing enough SAMe, you might feel blue or have trouble sleeping. And according to the Center for Disease Control, an estimated 1 in 10 American adults say they are depressed. Supplementing with Doctor's Best SAMe can help and improve your quality of life.